Genomics allows individualize treatments for cancer patients, explains Dr. Howard Lim, medical oncologist, BC Cancer.

Breaking down cancer with genomics

Donor funding has played a pivotal role in advancing genomics research

“It was like a miracle.”

Trish Keating was diagnosed with colon cancer in 2010 and after surgery, chemotherapy and radiation treatment, she was told in 2013 when her cancer returned that it was terminal.

After enrolling in the Personalized Onco-Genomics (POG) Program at BC Cancer, the team of experts discovered Trish’s cancer was driven by a specific protein. They then identified and administered an existing blood pressure medication that is known to block pathways to that protein.

The results were rapid and dramatic: eight weeks after starting her new treatment, Trish was tumour-free.

“It’s still so hard to believe,” says Trish. “I was months away from death.”

Trish’s experience is just one example of how genomics – where experts deploy whole genome analysis to inform individual treatment planning for patients – is transforming cancer care for people across B.C.

“The use of genomics is trying to understand the blueprint – what we call the genome – to a cancer, and by understanding that blueprint we can then start to individualize treatments for patients,” says Dr. Howard Lim, medical oncologist, BC Cancer. “Genomics will change not only how we treat cancer, but also how we detect and prevent cancer.”

Cancer genomes are as unique as a fingerprint, and no two genomes are identical. Therefore, says Dr. Lim, cancer treatment can no longer be one-size-fits-all.

“We’re beginning to understand that not all cancers are the same and certain ones respond differently to different treatments, or don’t respond at all to particular treatments,” he says. “With this knowledge we can begin to tailor the type of chemotherapy or targeted agents that we can use for treating specific cancers.”

Dr. Lim says donor funding has played a pivotal role in advancing genomics research, which is also the fundraising focus of BC Cancer Foundation’s Inspiration Gala on Nov. 2.

“The basic science we do to help further all of this research is thanks to donor support – it makes a huge impact to all of us in the clinic,” says Dr. Lim. “In fact, a lot of the research and treatments we’ve moved forward with is because of BC Cancer Foundation donors.”

You can help transform the standard of cancer care with genomically informed treatments for British Columbians facing cancer. Learn more at www.bccancerfoundation.com.

Comments are closed

Just Posted

Pacific FC, Dodd’s Furniture team up for local food banks

CPL team offering one free ticket to Oct. 2 game for two non-perishable food donations

Historic camp celebrates 75 years in Sooke

Camp Barnard donated to Scouts Canada in 1944

Arguments ramp up against proposed Sooke daycare

Proposed Church Road facility clears the latest hurdle

UVic announces review into circumstances of fatal bus crash

Upcoming student trip on the same route not cancelled

Hundreds gather at fundraising kickoff for ‘Kings Park’ purchase

Campaign to raise $2.75 million for the District of Saanich underway

Third instance of Trudeau in skin-darkening makeup emerges

Another instance of Trudeau using makeup to darken his face has emerged, within 24 hours of the first

Crime Stoppers most wanted for Greater Victoria for the week of September 17

Greater Victoria Crime Stoppers is seeking the public’s help in locating the… Continue reading

POLL: Should the province step in to upgrade the road to Bamfield?

The death of two University of Victoria students on a bus bound… Continue reading

21 years: Grand Chief Stewart Philip to continue leading B.C. Indian Chiefs union

Grand Chief Stewart Phillip acclaimed as president of Union of BC Indian Chiefs

Murder charges laid after body pulled from Fraser River ID’ed as missing man

Accused also face one count each of attempted murder in connection with Rudy Johnson Bridge incident

B.C. MLA’s former constituency assistant charged with fraud, breach of trust

Charges announced Sept. 19 more than two years after Martin fired Desmond Devnich for alleged thefts

B.C. salmon farm inspection deal reached with Indigenous people

Monitoring to determine if any Broughton region farms stay open

RCMP seize $1.9 million in B.C. traffic stop

The driver and passenger were detained under the Controlled Drugs and Substances Act

Yearbook photo surfaces of Trudeau wearing ‘brownface’ costume in 2001

The report describes the occasion as an ‘Arabian Nights’-themed gala event

Most Read